(2E)-2-(benzenesulfonylhydrazinylidene)acetic acid

(2E)-2-(benzenesulfonylhydrazinylidene)acetic acid - Names and Identifiers

Name	Hydroxyquinolinecarboxylicacid
Synonyms	Nsc27445 Hydroxyquinolinecarboxylicacid hydroxyquinolinecarboxylicacid 8-Hydroxyquinoline-7-carboxylic 8-HYDROXY-7-QUINOLINECARBOXYLIC ACID 8-hydroxyquinoline-7-carboxylic acid 8-Hydroxy-7-quinolinecarboxylic acid 8-HYDROXYQUINOLINE-7-CARBOXYLIC ACID 7-Quinolinecarboxylic acid, 8-hydroxy- ethyl 8-hydroxyquinoline-7-carboxylate (2E)-2-(benzenesulfonylhydrazinylidene)acetic acid
CAS	19829-79-9
EINECS	224-828-9
InChI	InChI=1/C12H11NO3/c1-2-16-12(15)9-6-5-8-4-3-7-13-10(8)11(9)14/h3-7,14H,2H2,1H3

(2E)-2-(benzenesulfonylhydrazinylidene)acetic acid - Physico-chemical Properties

Molecular Formula	C10H7NO3
Molar Mass	189.17
Density	1.480±0.06 g/cm3(Predicted)
Melting Point	208-209 °C (decomp)
Boling Point	384.7±32.0 °C(Predicted)
Flash Point	168°C
Solubility	DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
Vapor Presure	1.66E-05mmHg at 25°C
Appearance	Solid
Color	Pale Yellow to Pale Beige
pKa	1.34±0.30(Predicted)
Storage Condition	-20°C Freezer, Under inert atmosphere
Refractive Index	1.631

(2E)-2-(benzenesulfonylhydrazinylidene)acetic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

(2E)-2-(benzenesulfonylhydrazinylidene)acetic acid - Introduction

It is an organic compound with the chemical formula C10H7NO3. Its nature is as follows:

Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: approximately 210-215 ° C.
-Solubility: Soluble in water, alcohol and Ketone solvents, slightly soluble in ether solvents.

Use:
-is a potential drug intermediate, commonly used in the synthesis of various natural products, drugs and pesticides.
-It is also used in the field of metal catalytic reactions and coordination chemistry in organic synthesis, as well as in the preparation of photoelectric functional materials.

Method:
-A commonly used preparation method is to oxidize quinoline with hydrogen peroxide to 8-hydroxyquinoline, and then react it with chloroacetic anhydride to form quinoline.

Safety Information:
-G has limited toxicity data, and it is considered to be a low-toxic compound under general experimental conditions.
-In handling and storage, appropriate precautions need to be taken to avoid inhalation, skin contact and ingestion.

Last Update：2024-04-09 02:00:44